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CORTICOTROPIN RELEASING FACTOR
Descriptors Found:
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DeCS
Descriptor
English
:
Corticotropin-Releasing Hormone
Descriptor
Spanish
:
Hormona Liberadora de Corticotropina
Descriptor
Portuguese
:
Hormônio Liberador da Corticotropina
Synonyms
English
:
ACTH-Releasing Factor
CRF (ACTH)
Corticoliberin
Corticotropin-Releasing Factor-41
ACTH Releasing Factor
ACTH Releasing Hormone
Corticotropin Releasing Factor
Corticotropin Releasing Factor 41
Corticotropin Releasing Hormone
Corticotropin Releasing Hormone 41
ACTH-Releasing Hormone
Corticotropin-Releasing Factor
Corticotropin-Releasing Hormone-41
CRF-41
Tree Number:
D06.472.699.327.740.140
D12.644.400.400.740.140
D12.644.548.365.740.140
D12.776.631.650.405.740.140
Definition
English
:
A peptide of about 41
amino acids
that stimulates the release of
ADRENOCORTICOTROPIC HORMONE
. CRH is synthesized by
neurons
in the PARAVENTRICULAR NUCLEUS of the
HYPOTHALAMUS
. After being released into the pituitary portal circulation, CRH stimulates the release of ACTH from the
PITUITARY GLAND
. CRH can also be synthesized in other
tissues
, such as
PLACENTA
;
ADRENAL MEDULLA
; and
TESTIS.
Indexing Annotation
English
:
DF: CRH
Pharmacological Action:
Hormones
See Related
English
:
Receptors, Corticotropin-Releasing Hormone
History Note
English
:
90; was CORTICOTROPIN RELEASING HORMONE 1974-89; was CORTICOTROPIN RELEASING FACTOR 1968-73
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
22405
Unique Identifier:
D003346
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
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